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Nucleic acid inhibitor : ウィキペディア英語版 | Nucleic acid inhibitor
A nucleic acid inhibitor is a type of antibacterial that acts by inhibiting the production of nucleic acids. There are two major classes: DNA inhibitors and RNA inhibitors.〔http://www.ccsf.edu/Departments/Biology/ctoebe/antibiotics.htm〕 The antifungal flucytosine acts in a similar manner. ==DNA inhibitors== DNA inhibitors (such as the quinolones, acting upon DNA gyrase as a topoisomerase inhibitor)〔 Another group of DNA inhibitors, including nitrofurantoin and metronidazole, act upon anaerobic bacteria. These act by generating metabolites that are incorporated into DNA strands, which then are more prone to breakage. These drugs are selectively toxic to anaerobic organisms, but can affect human cells.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Nucleic acid inhibitor」の詳細全文を読む
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